Salivary Acetylcholinesterase Activity Is Increased in Parkinson’s Disease: A Potential Marker of Parasympathetic Dysfunction

Table 2

Comparison of clinical and biochemical parameters in patients and controls.

	Controls; ()	PD patients; ()	value
Sniffin’ Sticks	11.1 ± 2.7	6.8 ± 2.6	<0.001
FM100 error score	63 ± 41.1	89 ± 56.2	0.03
RBDSQ	2.5 ± 2.3	4.3 ± 2.9	0.005
ROME III-LGI	4.1 ± 5.9	11.5 ± 11.4	0.002
ROME III-constipation	1.5 ± 2.3	5.6 ± 5.3	<0.001
DRS	0.6 ± 1.6	2.6 ± 3.1	<0.001
Salivary flow (mL/min)	0.36 ± 0.2	0.25 ± 0.2	0.02
Total protein (mg/mL)	1.2 ± 0.5	1.8 ± 1.1	0.002
AChE activity (a.u.)	0.19 ± 0.15	0.36 ± 0.22	<0.001
AChE/total protein ratio (a.u./mg)	0.17 ± 0.12	0.23 ± 0.14	0.04

ROME III-LGI: lower GI symptoms questionnaire; ROME III-constipation: questions 9–14 from ROME III-LGI. All values are mean ± SD.