MRI Correlates of Parkinson’s Disease Progression: A Voxel Based Morphometry Study

Table 1

Sociodemographic and clinical characteristics of the two study groups. Values denote mean (± standard deviation) or numbers of subjects.

	PD patients	Controls
Sociodemographics
Age (years)	60.5 (±7.7)	64.6 (±4.8)
Sex (male/female)	12/8	8/7
Education (years)	9.75 (±3.76)	11.3 (±3.19)
Clinical characteristics
Duration of illness (years)	5.17 (±4.14)
Age at diagnosis (years)	55.20 (±8.44)
Baseline (test) OFF-drug
UPDRS I	2.50 (±1.84)
UPDRS II	8.55 (±3.88)
UPDRS III	26.6 (±7.12)
H&Y scale	2.42 (±0.25)
Retest OFF-drug
UPDRS I	2.61 (±1.50)
UPDRS II	9.76 (±5.21)
UPDRS III	22.46 (±6.02)
H&Y scale	2.71 (±0.26)
Equivalent dose of dopaminergic drug
Test (mg)	473.5 (±238.0)
Retest (mg)	650.3 (±272.9)