Minimal Clinically Important Difference on Parkinson’s Disease Sleep Scale 2nd Version

Table 3

Best cutoff values discriminating minimal clinically important differences for PDSS-2 determined by receiver operating characteristic analysis.

	ROC curve cutoff	Sensitivity	Specificity	+LR	−LR	AUC	Significance
PGI-I
A little better	<−3	54.00	51.40	1.11	0.89	0.523	0.046
The same	NA
A little worse	≥2	50.98	65.42	1.47	0.75	0.613	0.023

AUC: area under the curve; +LR: positive likelihood-ratio; −LR: negative likelihood-ratio; PDSS-2: Parkinson’s Disease Sleep Scale 2nd version; PGI-I: Patient-Rated Global Impression of Improvement; ROC: receiver operating characteristic analysis.