Research Article

Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson’s Disease Patients

Table 1

Genotypic and demographic characteristics of the six dermal fibroblast donors used in this study.

IdentifierLab IDParkin mutationGenderAAO (years)AAR (years)PD duration (years)

PD patients
 P153.44Deletion exon 3-4 homFemale273912
 P2P2Deletion exon 4 homFemale275427
 P3P3Deletion exon 4 homFemale275225
Controls
 Ct1WT2n/aFemalen/a62n/a
 Ct2WT3n/aFemalen/a56n/a
 Ct3WT4n/aFemalen/a44n/a

The age of the donor at the time of skin punch biopsy. AAO, age at onset; AAR, age at recruitment; hom, homozygous; n/a, not applicable; PD, Parkinson’s disease.