Abnormal Echogenicity of the Substantia Nigra, Raphe Nuclei, and Third-Ventricle Width as Markers of Cognitive Impairment in Parkinsonian Disorders: A Cross-Sectional Study
Table 1
Patient characteristics, divided into group of diagnosis.
Parkinson’s disease ()
Atypical parkinsonism ()
value
Age years (SD)
68.54 (9.27)
71.85 (9.31)
0.05
Men (%)
50 (70)
43 (80)
0.20
Disease duration months mean (SD)
29.08 (46.78)
40.39 (41.69)
0.16
UPDRS total score mean (SD)
24.03 (10.98)
30.26 (17.24)
0.02
UPDRS motor score mean (SD)
13.10 (6.00)
15.63 (8.52)
0.07
SCOPA-COG mean (SD)
23.83 (5.93)
21.41 (7.85)
0.05
Presence of cognitive impairment %
37.50
51.85
0.11
Hyperechogenic substantia nigra %
41.28
46.30
0.50
Hypoechogenic raphe nuclei %
21.74
20.00
0.85
Third-ventricle width mm (SD)
5.78 (2.28)
5.31 (2.38)
0.45
SCOPA-COG = scales for the outcome of Parkinson’s disease cognition, UPDRS = Unified Parkinson’s Disease Rating Scale.
