Research Article

Deep Brain Stimulation Frequency of the Subthalamic Nucleus Affects Phonemic and Action Fluency in Parkinson’s Disease

Table 4

Comparisons of the verbal fluency tasks and UPDRS-III between the different frequencies of SNT-DBS.

Variables60 Hz130 HzDifferenceCI 95%
Mean ± SEMean ± SE

UPDRS III, total34.33 ± 4.7435.44 ± 4.30−1.11−9.38–7.150.792
UPDRS III, tremor2.72 ± 1.202.00 ± 1.090.72−2.19–3.630.627
UPDRS III, gait1.28 ± 0.261.61 ± 0.33−0.33−0.80–0.130.157
UPDRS III, pull test1.28 ± 0.291.83 ± 0.34−0.56−1.12–0.000.052
Phonemic VF, P16.53 ± 1.8212.47 ± 1.564.051.65–6.45
Phonemic VF, FAS26.84 ± 3.3623.79 ± 2.793.050.10–6.00
Semantic VF, animals13.70 ± 1.2012.89 ± 1.080.89−0.76–2.550.290
Unconstrained VF29.63 ± 2.9227.58 ± 2.591.95−1.76–5.870.292
Action VF9.94 ± 1.227.56 ± 1.942.390.77–4.00

CI: confidence interval; SE: standard error; UPDRS: Unified Parkinson’s Disease Rating Scale; VF: verbal fluency; .