LRRK2 G2019S Mutation: Prevalence and Clinical Features in Moroccans with Parkinson’s Disease

Table 3

Clinical features of G2019S carrier and noncarrier patients.

	G2109S carriers	G2019S noncarriers	p value
	(n = 41)	(n = 59)
Initial symptom			0.019
	14 (34.1)	9 (15.3)
	11 (26.8)	31 (52.5)
Tremor and	16 (39)	19 (32.2)
Clinical phenotype			0.012
Akinetic-rigi	10 (24.4)	10 (16.9)
Tremor-dominan	7 (17.1)	27 (45.8)
	24 (58.5)	22 (37.3)
	9 (21.9)	3 (5.1)	0.011
Gait	21 (51.2)	23 (39)	0.225
Postural	17 (41.5)	29 (49.2)	0.448
UPDRS III	11 [6.5–19]	11 [6–21]	0.858
H-Y	2 [1–4]	3 [1–4]	0.875
	727.9 [500–1100]	500 [300–800]	0.002
	25 (61)	29 (49.2)	0.243
	23 (56.1)	15 (25.4)	0.002
Urinary	30 (73.2)	48 (82.8)	0.253
	21 (51.2)	31 (52.5)	0.896
Orthostatic	16 (39.0)	29 (49.2)	0.318
	22 (53.7)	31 (52.5)	0.912
Psychiatric	25 (61.0)	28 (47.5)	0.184
Cognitive	26 (63.4)	26 (44.1)	0.059
Sleep	22 (53.7)	19 (33.3)	0.046

Data are (percentage) and [interquartile range]. Significant p values are in bold.