Mutation Analysis of HTRA2 Gene in Chinese Familial Essential Tremor and Familial Parkinson’s Disease

Table 3

Statistics of minor allele frequency (MAF).

RS number	Position	Function	MAF				ExAC/1000	HWE ()	OR (95% CI), value
			FET	FPD	ET-PD	Control	Genomes MAF		FET versus control	FPD versus control
rs2241027	Intron	Uncertain	0.33	0.29	0.33	0.28	0.05/0.10	0.82	1.28 (0.83–1.96), 0.26	0.80 (0.47–1.35), 0.40
rs2241028	Exon-intron boundary	Uncertain	0.14	0.16	0.23	0.21	0.06/0.07	0.71	1.08 (0.70–1.66), 0.73	0.70 (0.42–1.16), 0.17

HWE for controls.