Author Country/Region Year Design Costs studied Perspective Value/year Comments Yoritaka et al. [40 ] Japan 2016 715 SPO D S 5,828 Direct cost Martínez-Martin et al., [44 ] Spain 2015 174 PO/BU D/I S 13,720.24/year 4 Magnitude of disease and quality of life Tamás et al. [39 ] Hungary 2014 110 PE/BU D/I/OOP S/CH 6,831 Costs of illness and quality of life Kowal et al. [22 ] USA 2013 630,000 PE D/I S 22,800 Economic load current and projected (by 2050) in the USA Zhao et al. [19 ] Singapore 2013 195 PE/MK/BU D/I S 68,519 (over the lifetime period) Cost of illness Johnson et al. [41 ] USA 2013 1,151 RE D/I CS 43,506 PDINST (cohort) Cost of illness x several cohorts Bhattacharjee and Sambamoorthi [29 ] USA 2013 350 RE D/OOP S 15,404 Cost of illness/over expenditure associated with PD Kaltenboeck et al. [23 ] USA 2012 25,577 RE D G 78,042 (ambulatory pac. PD) Survival rates and costs of patients of health programs Bach et al. [43 ] Germany 2012 1,449 PE D/I G 6.00 (2190) to 12.69 (4631.85) Cost of illness/drugs/comorbidities Lökk et al. [25 ] Sweden 2012 4,163 PE/RE D S 9,333 Cost of illness/drugs Johnson et al. [20 ] USA 2011 278 PO I S/CH/CS 569,393 (45 years), 188,590 (55), 35,496 (65), 2,451 (75) (from 40 to 79 years) Indirect costs Jennum et al. [26 ] Denmark 2011 13,400 RE/PO D/I S 7,763 Cost of illness Zhao et al. [38 ] Singapore 2011 195 PE/BU D/I/OOP S 10,129 Cost of illness von Campenhausen et al. [45 ] Europe (6 countries) 2011 486 PE/RE/BU D/I/OOP S 2,968 to 11,124 Cost of illness Winter et al. [30 ] Italy 2010 70 PO/BU D/I/OOP S 19,574 Cost of illness/drugs Winter et al. [46 ] Germany 2010 145 PO/PE/BU D/I/OOP G 22,763 Cost of illness Winter et al. [47 ] Germany 2010 145/133 PE/RE D/I S 21,138 to 35,864 Cost of illness Winter et al. [32 ] Czech Rep. 2009 100 PE/RE/BU D/I S/CH/P 12,483 Cost of illness Winter et al. [37 ] Russia 2009 100 PE/PO/BU D/I S/CH 5,935 Cost of illness Vargas et al. [42 ] Brazil 2008 144 PE/PO/BU IN NA NA Resource use X incapacity McCrone et al. [33 ] UK 2007 175 PE/RE D/OOP CS/P 19,861 Cost of illness Leibson et al. [35 ] USA 2006 92 PE/RE D NA Unclear Cost of illness per groups Ragothaman et al. [36 ] India 2006 175 PE/PO D S 707 Cost of illness/direct costs Wang et al. [48 ] China 2006 190 PE/RE/BU D/I S 925 Cost of illness Vossius et al. [31 ] Germany/Norway 2006 438 PE/RE/PO D S 2,389 (Germany), 1,620 (Norway) Cost of PD drugs Noyes et al. [27 ] USA 2006 717 PE/RE D/OOP S/P 18,528 Cost of illness/drugs/medicare Cordato et al. [28 ] Australia 2006 12 PE/PO D/I S 5,380 Cost of illness Huse et al. [24 ] USA 2005 20,016 PE/RE D CS 10,037 Cost of illness Spottke et al. [34 ] Germany 2005 145 PE/PO D/I/OOP S/G/P 22,723 ± 28,297 Cost of illness Cubo et al. [21 ] Spain 2005 23,417 RE Int. G NA Years of life lost
