Research Article

Deep Brain Stimulation of Hemiparkinsonian Rats with Unipolar and Bipolar Electrodes for up to 6 Weeks: Behavioral Testing of Freely Moving Animals

Table 1

Experimental design. The number of rats refers to the group sizes at the time of the apomorphine-induced rotation tests.

Group name6-OHDA lesionElectrodeDBS durationNumber of animals

Naive_3 d/3 w10
Naive_sham_3 wBipolar9
6-OHDA_sham_3 d/3 w+Bipolar7
Sham_bi_3 dShamBipolar3 days9
Sham_bi_3 wShamBipolar3 weeks10
Sham_uni_6 wShamUnipolar6 weeks7
6-OHDA_bi_3 d+Bipolar3 days7
6-OHDA_bi_3 w+Bipolar3 weeks5
6-OHDA_uni_3 d+Unipolar3 days13
6-OHDA_uni_3 w/3 w + 3 d off+Unipolar3 weeks11
6-OHDA_uni_6 w+Unipolar6 weeks7
6-OHDA_uni_3 w + 3 w off+Unipolar3 weeks8