Research Article
Deep Brain Stimulation of Hemiparkinsonian Rats with Unipolar and Bipolar Electrodes for up to 6 Weeks: Behavioral Testing of Freely Moving Animals
Table 1
Experimental design. The number of rats refers to the group sizes at the time of the apomorphine-induced rotation tests.
| Group name | 6-OHDA lesion | Electrode | DBS duration | Number of animals |
| Naive_3 d/3 w | − | — | — | 10 | Naive_sham_3 w | − | Bipolar | — | 9 | 6-OHDA_sham_3 d/3 w | + | Bipolar | — | 7 | Sham_bi_3 d | Sham | Bipolar | 3 days | 9 | Sham_bi_3 w | Sham | Bipolar | 3 weeks | 10 | Sham_uni_6 w | Sham | Unipolar | 6 weeks | 7 | 6-OHDA_bi_3 d | + | Bipolar | 3 days | 7 | 6-OHDA_bi_3 w | + | Bipolar | 3 weeks | 5 | 6-OHDA_uni_3 d | + | Unipolar | 3 days | 13 | 6-OHDA_uni_3 w/3 w + 3 d off | + | Unipolar | 3 weeks | 11 | 6-OHDA_uni_6 w | + | Unipolar | 6 weeks | 7 | 6-OHDA_uni_3 w + 3 w off | + | Unipolar | 3 weeks | 8 |
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