Clinical Study

Rivastigmine as a Symptomatic Treatment for Apathy in Parkinson’s Dementia Complex: New Aspects for This Riddle

Table 4

6-month NPI results; in the first and third rows it has been reported the within group comparison with baseline.

Subitems NPINumber of patients/48 (%) within groups
(6 months versus baseline)
Frequency × severityCaregiver distress

hallucinations16 (33%) ()21 (NS)
Delusions7 (15%) ()11 (NS)
Agitation/aggression4 (8%) (NS)21 (NS)
Dysphoria/depression17 (35%) ()31 ()
Anxiety20 (42%) ()41 ()
Irritability4 (8%) ()31 ()
Disinhibition1 (2%) ()21 ()
Euphoria2 (4%) (NS)21 ()
Apathy30 (62%) ()84 (NS)
Aberrant motor behavior2 (4%) (NS)22 ()
Sleep behavior change4 (8%) ()23 ()
Appetite change1 (2%) ()22 ()