Clinical Study

Rivastigmine as a Symptomatic Treatment for Apathy in Parkinson’s Dementia Complex: New Aspects for This Riddle

Table 5

12-month NPI results. In the first and third rows it has been reported the within group comparison with baseline and with 6-month results.

Subitems NPINumber of patients/48 (%) within groups
(12  months versus baseline)
(12  months versus 6 months)
Frequency × severityCaregiver distress
within groups
(12 months versus baseline)
(12 months versus 6 months)

Hallucinations15 (31%)
()
(NS)
21
(NS)
(NS)

Delusions8 (17%)
()
(NS)
11
(NS)
(NS)

Agitation/aggression3 (8%)
(NS)
(NS)
21
(NS)
(NS)

Dysphoria/depression19 (40%)
()
(NS)
31
()
(NS)

Anxiety21 (44%)
()
(NS)
41
()
(NS)

Irritability1 (2%)
()
()
31
()
(NS)

Disinhibition0 (0%)
()
()
01
()
(NS)

Euphoria0 (0%)
()
()
01
()
(NS)

Apathy33 (69%)
()
(NS)
88
(NS)
(NS)

Aberrant motor behavior1 (4%)
(NS)
(NS)
11
()
(NS)

Sleep behavior change5 (10%)
()
(NS)
32
()
(NS)

Appetite change1 (2%)
()
(NS)
11
()
(NS)