Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s Disease

Table 1

Sample characteristics and performance in the neuropsychological tests (raw scores).

Variables	PD-MCI ()		CO-MCI ()
	Amnestic ()	Nonamnestic ()	Amnestic ()	Nonamnestic ()
	Mean (sd)	Mean (sd)	Mean (sd)	Mean (sd)
Age (years)	61.61 (6.867)	61.62 (8.047)	61.48 (6.901)	61.24 (6.549)	0.999
Education level (years)	9.61 (4.153)	10.62 (3.556)	11.43 (3.501)	11.24 (4.300)	0.385
Sex% (male/female)	56.5/43.5	71.4/28.6	30.4/69.6	28.6/71.4	—
Vascular risk factor% (yes/no)	40.0/60.0	21.4/78.6	37.5/62.5	54.5/45.5	—
MMSE	27.13 (2.201)	27.81 (1.401)	27.39 (1.158)	27.76 (1.221)	0.559
MoCA	22.0 (3.849)	22.86 (3.410)	21.35 (3.725)	22.67 (3.596)	0.619
BDI	9.52 (6.186)	5.67 (4.386)	8.35 (4.978)	7.10 (4.679)	0.168
Duration of symptoms (months)	76.17 (35.006)	73.14 (38.681)	—	—
L-dopa equivalent dose (mg)	673.09 (295.904)	1284.76 (3072.005)	—	—
UPDRS-III	25.96 (34.458)	67.62 (86.098)	—	—
PDQ39 (total)	31.29 (13.768)	21.89 (13.547)	—	—
Schwab-England scale	82.17 (7.359)	87.14 (5.606)	—	—
	4.65 (1.152)	5.67 (1.653)	5.26 (1.054)	5.81 (1.250)	0.025
	7.13 (1.140)	8.14 (1.108)	8.09 (0.996)	9.00 (0.949)	<0.001
	8.35 (1.071)	9.05 (1.024)	8.43 (1.376)	9.57 (0.598)	<0.001
	6.74 (1.888)	8.10 (1.640)	8.26 (1.137)	8.95 (0.973)	<0.001
	4.04 (0.976)	4.62 (1.322)	4.57 (1.647)	5.76 (1868)	0.010
	3.83 (1.466)	5.19 (1.601)	4.65 (1.824)	5.33 (2.129)	0.015
	3.96 (2.440)	7.71 (2.704)	6.57 (3.273)	8.71 (2.704)	<0.001
	3.87 (2.181)	8.10 (2.948)	6.52 (3.475)	10.0 (2.588)	<0.001
	10.57 (5.558)	18.90 (7.516)	17.48 (7.609)	17.90 (5.957)	<0.001
	0.50 (0.261)	0.71 (0.172)	0.70 (0.298)	0.75 (0.167)	0.008
	4.13 (3.912)	10.71 (2.883)	5.09 (4.709)	11.14 (2.833)	<0.001
TMT	68.75 (20.914)	66.71 (19.587)	55.82 (18.213)	49.64 (21.135)	0.003
TMT	231.12 (128.926)	186.83 (79.737)	168.16 (99.767)	147.59 (66.065)	0.028
GCA% ((0) = none/(1) = mild/(2) = moderate/(3) = severe)	30.4/52.2/17.4/0	38.1/57.1/4.8/0	26.1/60.9/13/0	33.3/57.1/9.5/0	—
MTA% ((0) = none/(1) = ↑ of choroid fissure/(2) = ↑ of temporal horn/(3) = ↓ hippocampus/(4) = ↓↓ hippocampus)	52.2/39.1/8.7/0/0	57.1/42.9/0/0/0	56.5/30.4/8.7/4.3/0	57.1/42.9/0/0/0	—
FAZEKAS% ((0) = none or single punctate lesion/(1) = multiple punctate lesions /(2) = confluency lesions/(3) = large confluent)	39.1/34.8/17.4/8.7	38.1/47.6/9.5/4.8	26.1/52.2/13.0/8.7	9.5/52.4/33.3/4.8	—

-Wallis test; -Whitney; Memory Test; ⁽¹⁾Incidental memory; ⁽²⁾Learning; ⁽³⁾Number of figures recalled after 1-minute visualization; ⁽⁴⁾Recall of memorized figures after 5 minutes; Auditory Verbal Learning Test; ⁽⁵⁾Retrieval of words presented in a list of 15 substantives; ⁽⁶⁾Retrieval of words included in the interference list of 15 new substantives; ⁽⁷⁾Number of words memorized from list A without reread; ⁽⁸⁾Number of words memorized from list A, without reread, after 20-minute interval; ⁽⁹⁾Leaning curve of the words during attempts A1 to A5; ⁽¹⁰⁾Retroactive Interference (A6/A5); ⁽¹¹⁾Correct answers in recognition list; making test; ⁽¹²⁾trail A (time in seconds); ⁽¹³⁾trail B (time in seconds).