MRI-Guided Focused Ultrasound in Parkinson’s Disease: A Review

Table 2

Treatment outcomes of Parkinson’s disease patients that underwent MRgFUS treatment.

Authors & year	Target	Patients,	Motor UPDRS (Part II)
			Pretreatment	Post treatment; 3 months	Point reduction	Change (%)	Significance
Magara et al. 2014; Group 1	Pallidothalamic tract	4		16.5	2.3	12.2	NA
Magara et al. 2014; Group 2	Pallidothalamic tract	9		7.3	11.4	61.0
Schlesinger et al. 2015	Thalamotomy	7	27.0	19.7	7.3	27.0
Na et al. 2015	Pallidotomy	1	10	5	5	50	NA
Zaaroor et al. 2017	Thalamotomy		24.9		11.5	46.2

modified, not validated version of the motor-UPDRS that scored only the treated side of the body to a maximal score of 56 instead of 108 points in the original scale.
the 12 patients in Zaaroor et al., 7 are the same patients as in Schlesinger et al.
at 6 months.