Dual-Task Performance in GBA Parkinson’s Disease

Table 2

Single- and dual-task performance.

	GBA-PD	iPD	value
Single-task condition
Walking speed [m/s]	0.85 (0.54–1.13)	1.07 (0.71–1.35)	0.038
Checking boxes [1/s]	1.03 (0.53–1.84)	1.56 (0.91–2.29)	0.059
Subtracting [1/s]	0.31 (0.05–0.49)	0.31 (0.16–0.71)	0.134
Dual-task condition
Walking speed while checking boxes [m/s]	0.75 (0.39–0.95)	0.97 (0.61–1.25)	0.024
Checking boxes while walking [1/s]	0.76 (0.00–0.95)	1.33 (0.95–2.17)	<0.0001
Walking speed while subtracting [m/s]	0.75 (0.51–0.95)	0.88 (0.63–1.35)	0.115
Subtracting while walking [1/s]	0.40 (0.07–0.71)	0.42 (0.23–0.78)	0.979

Values are given in median (range). A logistic regression analysis, with the motor part of the Unified Parkinson’s Disease Rating Scale and the Montreal Cognitive Assessment as covariables, including likelihood ratio was used to calculate values. Significance level was set at . GBA-PD = Parkinson’s disease patients carrying a heterozygous glucocerebrosidase mutation; iPD = idiopathic Parkinson’s disease.