Microarray Analysis of the Molecular Mechanism Involved in Parkinson’s Disease

Table 3

List of top 20 nodes with higher degree in transcription factor-target regulatory network.

Gene	Full name	Description	Degree
TFDP1	Transcription factor Dp-1	Down	62
ZBTB7A	Zinc finger and BTB domain-containing 7A	Up	55
OVOL1	Ovo-like transcriptional repressor 1	Up	46
SMAD1	SMAD family member 1	Down	45
QSOX1	Quiescin sulfhydryl oxidase 1	Down	44
GATA3	GATA-binding protein 3	Up	38
ENC1	Ectodermal-neural cortex 1	Down	6
FNDC3A	Fibronectin type III domain-containing 3A	Up	6
MID1	Midline 1	Down	6
PDE4D	Phosphodiesterase 4D	Down	5
ZNF362	Zinc finger protein 362	Up	5
CBLB	Cbl proto-oncogene B	Down	4
LARGE	LARGE xylosyl- and glucuronyltransferase	Up	4
TRPC4	Transient receptor potential cation channel subfamily C member 4	Down	4
CTBP2	C-terminal binding protein 2	Up	4
GLI3	GLI family zinc finger 3	Down	4
SCN3A	Sodium voltage-gated channel alpha subunit 3	Up	4
TAL1	TAL BHLH transcription factor 1, erythroid differentiation factor	Down	4
LRRN3	Leucine rich repeat neuronal 3	Up	3
MAST4	Microtubule-associated serine/threonine kinase family member 4	Up	3

Transcription factor.