CLOCK 3111T/C Variant Correlates with Motor Fluctuation and Sleep Disorders in Chinese Patients with Parkinson’s Disease

Table 3

Binary logistic regression of association between sleep disorders and CLOCK 3111T/C variant.

Variable	OR	95% CI	value
3111T/C variant	1.130	1.007–1.268	0.037^a
Age (years)	1.008	0.989–1.028	0.407
Gender	1.348	0.905–2.008	0.142
Disease duration (years)	1.039	0.971–1.111	0.266
Hoehn-Yahr stage	1.098	0.795–1.516	0.571
UPDRS II + III	1.044	1.022–1.066	0.000^b
Mean PIGD score	0.976	0.917–1.038	0.443
Depression	3.872	2.455–6.135	0.000^b
Response to levodopa	1.044	0.986–1.106	0.141

UPDRS: Unified Parkinson’s Disease Rating Scale; MMSE: Mini-Mental State Examination. ^a and ^b.