Parkinson’s Disease / 2018 / Article / Tab 4

Research Article

Serum Homocysteine Level in Parkinson’s Disease and Its Association with Duration, Cardinal Manifestation, and Severity of Disease

Table 4

Frequency of different clinical features of Parkinson’s disease based on serum levels of homocysteine.

Serum homocysteine level (mol/L)Parkinson’s disease features value

Duration of the disease (years)
≤55–10>10
≤2057 (87/7%)21 (77/8%)7 (87/5%)0.572
>208 (12.3%)6 (22.2%)11 (12.5%)

Cardinal manifestation of the disease
Postural instabilityTremorRigidityBradykinesia
≤202 (66.7%)53 (85.5%)11 (84/6%)19 (86.4%)0.841
>201 (33.3%)9(14.5%)2 (15.4%)3 (13.6%)

Severity of the disease based on modified Hoehn and Yahr staging
1-2 (mild)2.5-3 (moderate)>3 (severe)
≤2033 (94.3%)36 (81.8%)16 (76.2%)0.154
>202 (5.7 %)8 (18.2%)5 (23.8%)

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