Kinematic Metrics from a Wireless Stylus Quantify Tremor and Bradykinesia in Parkinson’s Disease

Table 2

GEE estimates and empirical standard errors, regressing kinematic measures on bradykinesia subscale, controlling for medication and DBS status.

	Estimate	SE	Z
RMSrest Vel (%)	6.94	14.01	0.50	0.62
RMSpostural Vel (%)	3.43	70.83	0.30	0.76
RMSSMT Acc (m/sec^2)	−0.135	0.01	−1.63	0.10
RMSSMT Vel (m/sec)	−7.30	1.98	−3.68	0.0002
Peak Acc (m/sec^2)	−10.75	6.18	−1.74	0.08
Peak Vel (m/sec)	−13.60	9.35	−1.45	0.15
Dwell time (sec)	0.04	0.01	3.33	0.0009
Frequency (Hz)	−1.86	0.48	−3.89	0.0001
CV dwell time (%)	−0.04	0.03	−1.53	0.013

Metric with a logarithmic relationship; significant metric (p < 0.05).