Research Article

Motor Improvement-Related Regional Cerebral Blood Flow Changes in Parkinson’s Disease in Response to Antiparkinsonian Drugs

Table 3

rCBF changes in response to antiparkinsonian drugs in the SN, LG, and MG and their correlation with motor improvement: a subgroup analysis.

GroupMean rCBF change indexr

(a) SN
Total 30 patients31.10 (SD 32.36)0.37
Subgroups
 PD-ND39.31 (SD 36.18)0.39
 PD-D21.72 (SD 24.14)0.16

(b) LG
Total 30 patients17.22 (SD 35.42)0.60
Subgroups
 PD-ND27.08 (SD 38.92)0.61
 PD-D5.95 (SD 26.81)0.47

(c) MG
Total 30 patients22.62 (SD 40.03)0.54
Subgroups
 PD-ND25.89 (SD 42.10)0.54
 PD-D18.88 (SD 37.17)0.56

. Abbreviations for VOIs: LG, lateral geniculate body; MG, medial geniculate body; SN, substantia nigra; PD-D, PD with dementia; PD-ND, PD without dementia; rCBF, regional cerebral blood flow; SD, standard deviation; VOI, volume of interest.