Clinical Study

A Randomized Crossover Pilot Study of Telemedicine Delivered via iPads in Parkinson’s Disease

Table 1

The literatures of telemedicine using the real-time videoconferencing system.

AuthorsYearNStudy designSystemResult

Hubble et al. [6]19939Nonrandomized, controlled (one time, 90 min time interval)Motor assessment by the video conference systemThe UPDRS score by the system was comparable with face-to-face assessment
Samii et al. [7]200634Longitudinal observational (follow-up care, 3 years)Videoconferencing system at homeParticipants rated the questionnaire positively, telemedicine saved travel time and cost
Hoffmann et al. [8]200812Randomized, controlled (one-time, simultaneous evaluation)Evaluation of motor and ADL via computer-based video conference systemThe system was valid to measure ADL and the UPDRS. Intra- and interrater reliabilities were high
Tindall et al. [17]200824Case series (4 days/week, 4 weeks)Delivery of LSVT via videophoneVocal loudness improved; satisfaction with the technology combined to make videophone-delivered therapy
Biglan et al. [11]20091Case report (6 visits/8 months)Live videoconferencing at the nursing homeImprovement in motor and cognitive symptoms (fewer dyskinesia, longer on time, improved MMSE); patient satisfied with the care
Fincher et al. [14]200936Randomized, controlled (one-time medication consultation)Medication consultation via desktop videophone (21) vs telephone (15)Videophones were significantly useful than telephones; satisfied more with videophones
Howell et al. [16]20093Case series (3 times/week, 4 weeks)Internet delivery of LSVTThe system was comparable
Constantinescu et al. [18]20101Case report (4 days/week, 4 weeks)Delivery of LSVT via PC-based videoconferencing systemImprovements in voice; satisfied with overall treatment
Dorsey et al. [12]201010Randomized, controlled (4 visit/6 months)Telemedicine visit to the nursing home and adult day care populations via notebook computer-based videoconferencing telemedicine care (6) vs usual care (4)Significant improvements in QOL and the UPDRS motor scale
Constantinescu et al. [19]201134Randomized, controlled (4 days/week, 4 weeks)Online delivery of LSVT via PC-based videoconferencing systemNoninferiority of the online LSVT modality was confirmed; high participant satisfaction was reported overall
Dorsey et al. [24]201320Randomized, controlled, two centers (7 months)Web-based videoconferencing (“virtual house call”) telemedicine (9) vs in-person care (11)The change in quality of life did not differ
Venkataraman et al. [15]201435Case series (one time)Specialist consultation for new patients via videoconferencing systemPatients satisfaction exceeded 90%
Qiang and Marras [30]201534Retrospective controlled studySatisfaction questionnaire was compared between the previous user of video-based telemedicine use (34) vs nonuser (103)Telemedicine reduced the cost; patients preferred combination of telemedicine and in-person visit
Dorsey et al. [20]2015166ObservationalVirtual research visit using web cameras and videoconferencing softwareOverall satisfaction with visit was 79% (neurologists) and 93% (participants)
Stillerova et al. [10]201611Nonrandomized, self-controlled (one time)MoCA test via video conference system (Skype; PC9, smartphone/tablet2)Result is not different; system was viable
Stillerova et al. [9]201611Nonrandomized, controlled (one time)Face-to-face vs videoconferencing software (Skype or Google Hangouts) using computers and webcams for evaluation of the MDS-UPDRSInternet-based videoconferencing may be useful
Wilkinson et al. [13]201686Dual-arm, randomized, controlled (12 month)Video telehealth visit home arm: 18 actives (tablet-PC), 18 controls; satellite clinic arm: 26 actives (Carts and web-come), 24 controlsHigh patient satisfaction, reduced travel burden, equal clinical outcomes
Barbour et al. [21]201616Long-term observational (over 3 years)Videoconferencing systemParticipants, families, subspecialists, and the nursing staff expressed uniformly high satisfaction

MMSE: Mini-Mental State Examination; LSVT: Lee Silverman Voice Treatment; MoCa: Montreal Cognitive Assessment.