Intestinal Levodopa/Carbidopa Infusion as a Therapeutic Option for Unresponsive Freezing of Gait after Deep Brain Stimulation in Parkinson’s Disease
Table 1
Clinical, demographic, and surgical data.
Patient
Sex
Age at the time of STN-DBS (years)
Time from diagnosis to STN-DBS (years)
Latency between surgery and unresponsive-FOG onset (months)
Mattis Dementia rating scale
Surgery complications
DBS ON/OFF until 24 h before LCIG
Daily time spent in OFF before LCIG (UPDRS item 39)
Functional impact of dyskinesias before LCIG (UPDRS item 33)
P1
F
67
11
20
Normal
No
OFF
3
2
P2
F
69
6
8
Normal
No
OFF
3
2
P3
F
57
11
10
Normal
Infection left electrode
ON
3
3
P4
F
64
10
48
Normal
No
ON
2
1
P5
F
66
12
2.5
Normal
No
ON
3
2
Median age (years) at the time of STN-DBS: 66 IQR (57–69). Median time (years) from diagnosis to STN-DBS: 11 IQR (6–12). Median latency (months) between surgery and unresponsive-FOG onset: 10 IQR (2.5–48). F = female; IQR = interquartile range.
