5-2-1 Criteria: A Simple Screening Tool for Identifying Advanced PD Patients Who Need an Optimization of Parkinson’s Treatment
Table 3
Strain, burden, mood, and QoL in patient’s principal caregiver of those patients with 5-2-1 criteria (n = 16) vs those with 5-2-1 negative criteria (n = 46).
5-2-1 positive (n = 16)
5-2-1 negative (n = 46)
value
CSI
4.3 ± 3
1.5 ± 1.6
<0.0001
High stress level (≥7)
31.2
0
0.001
ZCBI
28.4 ± 12.5
10.9 ± 9.8
<0.0001
Little or no burden (0–20)
25
82.6
<0.0001
Mild to moderate burden (21–40)
62.5
17.4
Moderate to severe burden (41–60)
12.5
0
Severe burden (61–88)
0
0
BDI-II
12.2 ± 7.2
6.2 ± 6.1
<0.0001
PQ-10
6.4 ± 1.5
7.1 ± 1.6
0.141
EUROHIS-QOL8
3.6 ± 0.5
3.8 ± 0.5
0.139
Quality of life
3.5 ± 0.6
3.8 ± 0.8
0.186
Health status
3.6 ± 0.6
3.6 ± 0.9
0.908
Energy
3.5 ± 0.7
3.8 ± 0.8
0.253
Autonomy for ADL
3.6 ± 0.8
3.8 ± 0.8
0.495
Self-esteem
3.4 ± 0.6
3.8 ± 0.7
0.057
Social relationships
3.7 ± 0.8
3.9 ± 0.6
0.252
Economic capacity
3.6 ± 0.9
3.9 ± 0.7
0.132
Habitat
4 ± 0.5
4.2 ± 0.6
0.283
Chi-squared and Mann–Whitney–Wilcoxon tests were applied. The results represent percentages or mean ± SD. ZCBI and CSI were classified in groups according to severity [27]. BDI-II, Beck Depression Inventory-II; CSI, Caregiver Strain Index; ZCBI, Zarit Caregiver Burden Inventoy.
