|
| Author and year | Type of study | Method to assess studies’ quality | Finding | Limits |
|
| Saltychev et al. [27] | Systematic review and meta-analysis (12 RCTs) | Cochrane Collaboration’s domain-based evaluation framework | No evidence for the superiority of PRT compared to other physical training | Some relevant studies could remain undetected because of the uncertain definition of PRT |
|
| Tillman et al. [28] | Systematic review and meta-analysis (7 RCTs) | PEDro scale | On measures of gait and balance no evidence to support or refute PRT prescription; in conjunction with balance and task-specific functional training to improve these measures | The reduced sample size, which has been selected for the feasibility of conducting a one-to-one, 6-week exercise intervention. |
|
| Chung et al. [29] | Systematic review and meta-analysis (7 RCTs) | PEDro scale | PRT (2-3 times per week, 8–10 weeks) can enhance strength, balance and motor symptoms in early—moderate PD. | No blinding of subjects, intervention therapist and outcome assessors in the most of the RCTs.
Outcome evaluation over short-term (8–14 weeks) |
|
| Roeder et al. [30] | Systematic review and meta-analysis (9papers) | 2 review authors using a customized form | Combining RT with other form of physical exercise could be most effective.
Not enough data available to evidence-based guidelines for resistance training prescription | Published reports did not provide sufficient details for judgment, then bias from selective reporting of results and from allocation concealment was difficult to determine;
Since much was unknown about the quality of most included studies, it impacts on conclusions drawn from this review which are not definitive. |
|
| Lima et al. [22] | Systematic review and meta—analysis (2 RCTs and 2 QRCTs.). | PEDro scale | Evidence to support PRT prescription in mild/moderate PD’s patients and to implemented it as an ordinary therapy in PD. | Only 4 studies included |
|
| Cruisckshank et al. [31] | Systematic review and meta-analysis (6RCTs + 3 non-RCTs about PD and 5RCTs + 2 non-RCTs about MS) | PEDro scale | Benefit in strength after RT, it has a positive effect on clinical disease progression and mobility.
High-quality trials are needed. | The heterogeneity of interventions and study outcomes in PD and MS trials |
|
| Uhrbrand et al. [32] | Systematic review and meta-analysis (9RCTs) | PEDro scale | Strong evidence in favor of muscle strength improving in PD.
Inconsistent findings are about balance, walking performance and quality of life improving.
PRT may positively impact UPDRS-III and quality of life. | Small sample size; short-term interventions (≤12 settimane) |
|
| Brienesse and Emerson [21] | Systematic review (3 RCTs and 2 non-RCTs.) | Modified version of PEDro scale | RCTs with a standardized and thorough reporting of intervention and functional outcomes are needed. | Methodological limitation in available papers (RCTs do not satisfy all of quality criteria); not well RT description/inadequate description of the training protocol. |
|
