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| Accuracy unknown | Uneven in type of information gathered |
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| Subjective | Contain redundancies in sections |
| Numerically nonlinear | Choice selections and section constructs differ |
| Ordinal scale with score meaning, level, differences, and divisions unknown | UPDRS Part II considered culturally biased |
| Unable to discriminate between disease categories of clinical relevance | Applicable to most, but not all, international urban settings |
| Scores cannot differentiate nor compare patients | Effects of age, gender, race, and ethnicity on ratings have not been examined |
| All score sections not reported | Limited utility in early disease stages |
| Completed in a limited timeframe (clinic visit) | Can be affected by prior patient activities, but not recorded |
| Questions difficult to read and understand, responses based on interpretation by rater and patient | No connection to clinical stages |
| Differences exist among interrater reliabilities | Inadequate instructions for raters |
| Based on physician’s experience, inexperience | Respondents may not answer appropriately, fear of score outcome, lower total scores |
| Anxiety, sleep disorders, fatigue, urinary disfunction, other symptoms not included | Nonmotor symptoms not clinically diagnosed |
| How to track comorbidities does not exist | Cannot be used as a severity measure of any behavior |
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