Research Article

Intraoperative Quantitative Measurements for Bradykinesia Evaluation during Deep Brain Stimulation Surgery Using Leap Motion Controller: A Pilot Study

Table 1

Results of FT task statistical analysis.

FT featuresPreoperativeIntraoperative-valueCorrelation with MDS-UPDRS item

Velocity ()
(mm/s)243.81 ± 93.43348.48 ± 103.670.014a−0.379
−0.07 ± 0.23−0.04 ± 0.140.709a−0.240
0.27 ± 0.080.23 ± 0.090.266a−0.010

Frequency ()
(Hz)1.74 (1.66, 2.39)2.12 (1.71, 2.54)0.286b−0.202
0.11 ± 0.130.05 ± 0.140.220a0.238
0.23 (0.13, 0.29)0.17 (0.11, 0.20)0.333b0.216

Amplitude ()
(mm)61.01 ± 18.6480.15 ± 15.240.004a−0.379
−0.17 ± 0.22−0.09 ± 0.110.362a−0.353
0.24 ± 0.090.18 ± 0.090.098a0.151

FT, finger tapping; Δ, change; CV, coefficient of variation; PD, Parkinson’s Disease; MDS-UPDRS-III, International Parkinson and Movement Disorders Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale. a: these P values were determined using paired t tests. b: these P values were determined using the Wilcoxon tests. Asterisks () indicate significant correlations between kinematic parameters and the score on the corresponding MDS-UPDRS item: ; .