Parkinson’s Disease

Research Article

Handgrip Strength and Anthropometry in Parkinson’s Disease at Diagnosis

Table 2

Bivariate correlations r ( value) between daytime P-cortisol levels and characteristics, including plasma phosphate and body composition variables at time of diagnosis.
 Patients N  = 75Controls N  = 25Male patients N  = 41Female patients N  = 34
Age, years0.226 (0.051)−0.047 (0.826)0.393 (0.011)0.024 (0.893)
Sex, M = 0, F = 1−0.077 (0.514)0.131 (0.542)——
UPDRS-total0.255 (0.028)—0.285 (0.071)0.202 (0.251)
UPDRS-III0.312 (0.006)—0.332 (0.034)0.276 (0.114)
H&Y0.136 (0.244)—0.162 (0.312)0.120 (0.500)
MMSE−0.058 (0.618)0.152 (0.490)−0.077 (0.633)−0.010 (0.954)
P-phosphate, (mmol/L)−0.355 0.002)−0.153 (0.475)−0.408 (0.008)−0.292 (0.094)
MNA-total−0.281 (0.015)−0.119 (0.618)−0.511 (0.001)−0.055 (0.759)
MNA-initial−0.308 (0.007)−0.029 (0.895)−0.332 (0.034)−0.320 (0.065)
MNA-final−0.106 (0.374)−0.198 (0.403)−0.453 (0.003)0.331 (0.064)
PAL−0.209 (0.072)0.064 (0.771)−0.148 (0.357)−0.271 (0.121)
HGS, left (kgf)−0.003 (0.977)−0.314 (0.145)−0.089 (0.581)−0.077 (0.667)
HGS, right (kgf)−0.033 (0.779)−0.218 (0.318)−0.133 (0.407)−0.117 (0.509)
Anthropometry
BMI (kg/m2)−0.132 (0.260)−0.082 (0.702)0.023 (0.886)−0.259 (0.140)
ECW (lit)−0.175 (0.132)−0.187 (0.383)−0.299 (0.057)−0.412 (0.015)
ICW (lit)−0.262 (0.023)−0.059 (0.783)−0.458 (0.003)−0.287 (0.100)
ECW/ICW ratio0.194 (0.096)−0.220 (0.302)0.362 (0.020)0.008 (0.965)
TBW (lit)−0.240 (0.038)−0.117 (0.585)−0.442 (0.004)−0.354 (0.040)
FFMI (kg/m2)−0.230 (0.047)−0.142 (0.509)−0.346 (0.027)−0.273 (0.118)
FM (%)0.153 (0.191)0.132 (0.537)0.513 (0.001)0.052 (0.770)
UPDRS = Unified Parkinson’s Disease Rating Scale. H&Y = Hoehn & Yahr. MNA = Mini Nutritional Assessment. PAL = physical activity level. HGS = handgrip strength (kgf). BMI = body mass index (kg/m2). ECW = extracellular water. ICW = intracellular water. TBW = total body water (ECW + ICW). FFMI = fat-free mass index (kg/m2). FM (%) = fat mass percent. The significance level is 95% CI ∗p<0.05.