Research Article

Impact of Gastrointestinal Symptoms on Health-Related Quality of Life in an Australian Parkinson’s Disease Cohort

Table 2

Analysis of associations between different measures of constipation and total PDQ-39 score in PD cohort.

Constipation measuresPDQ-39 total score
NaïveCorrected^
Interceptβ-coefficient valuesInterceptβ-coefficient values

Bristol stool chart36.766−1.550.28810.7191.3260.318
Frequency of defecation34.365−2.980.14615.5730.0430.981
Self-reported constipation25.55910.5580.00511.7317.5070.024
Constipation (combined)22.20814.375<0.00110.5759.6190.006

^corrected for LEDD and disease duration. PD: Parkinson’s disease. PDQ-39: Parkinson’s disease questionnaire—39. GSRS: Gastrointestinal Symptom Rating Scale.