Research Article

Nicotine Has a Therapeutic Window of Effectiveness in a Drosophila melanogaster Model of Parkinson’s Disease

Figure 6

Nicotine treatment increases the number descending climbs in homozygous park25 flies. Number of (a) drops or (b) descending climbs (see Methods for details) in nicotine-treated flies. Data are presented as mean and SEM. Results from a post hoc Tukey HSD analysis are shown. Asterisks inside the bars compare between the two genotypes at individual nicotine levels. , . The results of each data point are from at least four separate experiments with an n ≥ 56 flies.