Parkinson’s Disease

Animal Models of Parkinson's Disease 2012


Publishing date
08 Jun 2012
Status
Published
Submission deadline
09 Dec 2011

Lead Editor

1Department of Neuroscience for Neurodegenerative Disorders, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan

2Department of Physiology and Pharmacology, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211, USA

3Department of Physiology, National University of Singapore, Duke-NUS Graduate Medical School, Singapore 169857


Animal Models of Parkinson's Disease 2012

Description

Parkinson's disease (PD) is one of the most common movement disorders and is characterized by age-dependent dysfunction and degeneration of the midbrain dopaminergic neurons. Understanding of the pathogenic mechanism of PD has progressed with neurotoxin-induced PD model animals. Moreover, recent advances in human molecular genetics have led to the identification of several familial PD genes, including α-synuclein, parkin, PINK1, DJ-1, LRRK2, and ATP13A2. Analyses of model animals, in which mutations of these PD genes are introduced, promise to shed lights on the pathogenic mechanism underlying idiopathic PD as well as familial PD.

We particularly take an interest in manuscripts that report the molecular mechanisms of neurodegeneration, therapeutic challenges using model animals, development of new screening methods, and generation of new PD models. High-quality research articles related to the topic and reviews to summarize the most recent progresses are welcome. Moreover, papers dealing with new methods to detect degeneration of dopaminergic neurons as well as other cells would be of great interest. Main topics include, but are not limited to:

  • PD studies using vertebrate models
  • PD studies using invertebrate models
  • PD studies using other organisms
  • Drug screening using PD model organisms
  • Development of therapeutic strategies using PD model organisms
  • Development of experimental techniques

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/pd/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 729428
  • - Editorial

Animal Models of Parkinson's Disease 2012

Yuzuru Imai | Katerina Venderova | Kah-Leong Lim
  • Special Issue
  • - Volume 2012
  • - Article ID 938528
  • - Research Article

The Protective Effect of Minocycline in a Paraquat-Induced Parkinson's Disease Model in Drosophila is Modified in Altered Genetic Backgrounds

Arati A. Inamdar | Anathbandhu Chaudhuri | Janis O’Donnell
  • Special Issue
  • - Volume 2012
  • - Article ID 697564
  • - Research Article

A Novel, Sensitive Assay for Behavioral Defects in Parkinson's Disease Model Drosophila

Ronit Shaltiel-Karyo | Dan Davidi | ... | Daniel Segal
  • Special Issue
  • - Volume 2012
  • - Article ID 129605
  • - Research Article

An NR2B-Dependent Decrease in the Expression of trkB Receptors Precedes the Disappearance of Dopaminergic Cells in Substantia Nigra in a Rat Model of Presymptomatic Parkinson's Disease

Eduardo Riquelme | Jorge Abarca | ... | Gonzalo Bustos
  • Special Issue
  • - Volume 2012
  • - Article ID 296875
  • - Research Article

Patterns of Cell Activity in the Subthalamic Region Associated with the Neuroprotective Action of Near-Infrared Light Treatment in MPTP-Treated Mice

Victoria E. Shaw | Cassandra Peoples | ... | John Mitrofanis
  • Special Issue
  • - Volume 2012
  • - Article ID 128356
  • - Review Article

Genetic Rat Models of Parkinson's Disease

Ryan M. Welchko | Xavier T. Lévêque | Gary L. Dunbar
Parkinson’s Disease
 Journal metrics
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Acceptance rate22%
Submission to final decision119 days
Acceptance to publication18 days
CiteScore5.200
Journal Citation Indicator0.730
Impact Factor3.2
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