Altered Responses to Cold Environment in Urocortin 1 and Corticotropin-Releasing Factor Deficient Mice

Table 3

Female UCN1KO mice do not acclimatize to cold environment. Statistical comparison of average rectal temperatures, taken every 10 min during 2 h (10 to 13 measurements for each mouse, 3 to 8 animals in each group) in mice exposed 2 times to 4°C. The second time was performed 3 days after the first attempt. Statistical analysis was made using ANOVA followed by Student’s 𝑡-test.

Genotype	Sex	Attempt number	Rectal temperature (°C) means ± SD	(𝑛)	𝑃 values^(a)
WT	Males	1st	36.9 ± 0.8	7	<0.001
		2nd	37.4 ± 0.6	7
	Females	1st	37.3 ± 0.4	7	<0.001
		2nd	38.0 ± 0.4	3
UCN1KO	Males	1st	37.3 ± 0.7	6	<0.05
		2nd	37.8 ± 0.6	3
	Females	1st	37.8 ± 0.5	8	NS
		2nd	37.6 ± 0.5	6