The Potential Role of Hemopexin and Heme Oxygenase-1 Inducer in a Model of Sepsis

Table 1

Comparison between experimental groups regarding the coagulation parameters.

	Control group (CG)	Sepsis group (CLP)	CLP + Hm	CLP + HPx
Prothrombin time (seconds)	17.08 ± 0.2	13.6 ± 0.2	18.6 ± 0.4	15.9 ± 0.5
Partial thromboplastin time (seconds)	15.8 ± 0.04	9.2 ± 0.3	15.6 ± 0.2	12.1 ± 0.3
APC (IU/dL)	96.8 ± 2.2	59 ± 1.6	83 ± 0.6	75.5 ± 1.05

Data are presented as mean ± SEM (7–12 per group); one-way ANOVA was conducted and the results of post hoc least significance difference comparison were shown. Results are significant at . Significant versus control group, significant versus CLP, and significant versus CLP + Hm.
APC: activated protein C.