Bending forward and squatting down are two common physical tasks in everyday life and at work. This study determined the sEMG characteristics between erector spinae and vastus lateralis during bending forward and squatting down tasks by analyzing the regularity of variation in sEMG frequency domain index-median frequency (MNF) in healthy subjects. The results indicate that sEMG activities in erector spinae are significantly higher than those in the right vastus lateralis during bending forward task. Instead, in squatting down task, sEMG activities in the right vastus lateralis are significantly greater than those in erector spinae. It also shows that the fatigue degree of low back caused by trunk bending is much deeper than that by squatting down. The ratio scope of one-order fitting values of MNF between erector spinae and vastus lateralis ranges from 0.87 to 1.72 among 80&#x25; of subjects during bending forward task and ranges from 0.31 to 1.11 during squatting down task. This study provides certain theoretical basis for using the strength of low back in a proper way to avoid getting it hurt in daily physical activities.

Jinzhuang Xiao

Junmin Gao

Hongrui Wang

Kun Liu

Xincai Yang

The Surface EMG Characteristics between Erector Spinae and Vastus Lateralis during Bending Forward and Squatting Down Tasks

Background and Aims. Sepsis can evoke disseminated intravascular coagulation, resulting in multiple organ failure and death. Heme oxygenase-1 (HO-1) and hemopexin (HPx) can mediate cytoprotective mechanisms against these deleterious effects. This study aims to determine a role for HO-1 and HPx in coagulopathy induced by septic inflammation and define whether they can enhance the production of anti-inflammatory cytokine IL-10. Materials and Methods. 48 healthy male albino rats were divided equally into 4 groups: control group: animals subjected to laparotomy and bowel manipulation; CLP group: severe sepsis induced by cecal ligation puncture (CLP); CLP + hemin group: animals received single intraperitoneal injection of hemin (50&#x2009;&#xb5;mol/kg) 12&#x2009;h before sepsis induction; CLP + HPx group: animals received single HPx dose (150&#x2009;&#xb5;g/rat, i.v.) 30&#x2009;min before sepsis induction. Survival rates were calculated. Prothrombin time (PT), activated partial thromboplastin time (APTT), and activated protein C (APC), liver HO-1, serum, and liver IL-10 levels were measured, 48&#x2009;hrs after sepsis induction. Liver and lung were excised for histopathological examination. Results. Hemin and HPx administration upregulated liver HO-1 and IL-10. They prolonged PT, PTT and increased APC. They reduced the inflammatory infiltrate and thrombosis in liver and lung parenchyma. However, hemin was superior in controlling coagulopathy and HO-1 production, while HPx was more potent stimulant of IL-10 expression. Conclusions. Hemin and HPx have a potential beneficial effect in severe sepsis regarding coagulopathy and inflammation.

Passainte S. Hassaan

Radwa A. Mehanna

Abeer E. Dief

The Potential Role of Hemopexin and Heme Oxygenase-1 Inducer in a Model of Sepsis

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Physiology Journal

Table of Contents

Table of Contents: 2015

The Surface EMG Characteristics between Erector Spinae and Vastus Lateralis during Bending Forward and Squatting Down Tasks

The Potential Role of Hemopexin and Heme Oxygenase-1 Inducer in a Model of Sepsis