Diagnosis and Management of Pulmonary Arterial Hypertension

Table 2

World Health Organization Functional Class of PAH.

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Class I: Patients with PAH that causes no limitations on physical activities. Routine physical activity does not cause increased dyspnea, chest pain, fatigue, or presyncope.

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Class II: Patients with PAH that causes mild limitations on physical activities. Patients are comfortable at rest but routine physical activity results in increased dyspnea, chest pain, fatigue, or syncope.

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Class III: Patients with PAH that have marked limitations on physical activities. Patients are comfortable at rest, but less than routine physical activity results in dyspnea, chest pain, fatigue, or palpitations.

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Class IV: Patient with PAH that results in the inability to perform any physical activity without symptoms. These patients may have signs of right heart failure. Dyspnea with or without fatigue may be present at rest, and symptoms are increased by any physical activity.

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