Review Article

Postoperative Acute Exacerbation of IPF after Lung Resection for Primary Lung Cancer

Table 3

The risk predictors of the postoperative acute exacerbation.

AuthorPublished yearRisk predictors of postoperative AEIPF

Kumar et al. [13]2003Low %DLco (AEIPF+ versus AEIPF−; 48% versus 58%), Low % 𝐾 C O (58% versus 70%), High CPI (44 versus 33)
Koizumi et al. [15]2004PS > 2, CRP > 2 mg/dL, LDH > 400 IU/L,%TLC < 95%
Okamoto et al. [16]2004%VC < 80, LowDLco (value is not described)
Kushibe et al. [17]2007%VC < 80%
Watanabe et al. [18]2008None
Shintani et al. [20]2010%VC (<80.6%) and LDH (≥241 IU/L)

𝐾 C O : levels of carbon monoxide diffusion capacity corrected for alveolar volume;
CPI: composite physiological index; PS: performance status; TLC: total lung capacity;
DLCO: diffusing capacity of the lung for carbon monoxide.