The Effects of Gas Humidification with High-Flow Nasal Cannula on Cultured Human Airway Epithelial Cells
Figure 5
Proinflammatory mediator concentration in apical surface wash fluid from Calu-3 monolayers exposed to one of three levels of relative humidity: <20% (dry), 69% (noninterventional comparator), and >90% (HFNC). Secretion of interleukin (IL)-6 (5A) and IL-8 (5B) in the dry group was greater than the noninterventional comparator group and the HFNC groups at 8 hours (), with no difference between the noninterventional comparator group and the HFNC groups () and no difference between any groups at 4 hours (). Data are mean ± SEM. *Group effect (). §Time effect ().
