Research Article

Decreased Apoptotic Rate of Alveolar Macrophages of Patients with Idiopathic Pulmonary Fibrosis

Table 3

Apoptotic markers’ expression (CIA mean values) in patients before treatment and in control subjects.

Control group [CI]IPF group [CI]P

ApoptAg density100,1 124,8 0.030
ApoptAg area580,03 84,88 <0.001
ApoptAg (+) cells78,8 11,1 <0.001
Bcl-2 density149,8 151,7 0.883
Bcl-2 (+) cells48,2 21,3 0.030
Bax density134,6 131,0 0.771
Bax (+) cells65,4 72,3 0.711
Fas ligand density139,2 133,3 0.312
Fas ligand (+) cells49,3 71,0 0.172
Fas density163,5 151,3 0.291
Fas (+) cells23,1 29,8 0.461

: statistically significant.