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Pulmonary Medicine
Volume 2013, Article ID 929028, 10 pages
Research Article

Asthma and Wheezing Are Associated with Depression and Anxiety in Adults: An Analysis from 54 Countries

1Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, AB, Canada T6G 1C9
2Department of Emergency Medicine, University of Alberta, Edmonton, AB, Canada T6G 2B7
3Centre for Public Health Research, Massey University, Wellington Campus, P.O. Box 756, Wellington, New Zealand

Received 14 November 2012; Accepted 3 February 2013

Academic Editor: Stefano Centanni

Copyright © 2013 Kai On Wong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Asthma and depression are important public-health concerns worldwide. While some epidemiologic studies have shown asthma and wheezing to be associated with depression and anxiety, the patterns are unclear at the multinational level due to the lack of cross-study comparability. Our study examined the associations of self-reported asthma diagnosis and current wheezing with self-reported depression diagnosis and 30-day anxiety using an international survey. Methods. Using the 2002 World Health Survey, a standardized international survey conducted by the WHO, we estimated the associations between diagnosed asthma and current wheezing with diagnosed depression and 30-day anxiety via multiple logistic regressions for 54 countries worldwide. Results. Diagnosed depression and 30-day anxiety were associated with diagnosed asthma in 65% and 40% of the countries, respectively. Diagnosed depression and 30-day anxiety were associated with current wheezing in 83% and 82% of the countries, respectively. Conclusions. The association between asthma and depression was generally seen at the global level. These results indicated the importance of addressing the asthma-depression comorbidity as public-health and clinical management priorities, in order to improve the overall health of the countries.