Clinical Study

Tolerability of Nasal Delivery of Humidified and Warmed Air at Different Temperatures: A Randomised Double-Blind Pilot Study

Table 2

Tolerability Questionnaire results.

Individual question results

Median (minimum to maximum)
General comfort⁢Nasal interface weightNoise⁢Nasal passage comfortEase of breathing through nose
NHF 37CNHF 41CNHF 37CNHF 41CNHF 37CNHF 41CNHF 37CNHF 41CNHF 37CNHF 41C

2.5 (1 to 3) 3.0 (1 to 4)1.5 (1 to 3)2.0 (1 to 3)2.0 (1 to 3)3.0 (2 to 4)2.0 (1 to 3)2.0 (1 to 3)2.5 (1 to 4)3.0 (1 to 4)

Difference in proportion that scored 3 or above (95% CI), NHF 41C minus NHF 37C
General comfortNasal interface weightNoiseNasal passage comfortEase of breathing through nose

30% (1.6 to 58.4) 0% (−39.2 to 39.2) 20% (−4.8 to 44.8) 20% (−4.8 to 44.8) 20% (−4.8 to 44.8)

Free text comments#
InterventionDifficulty in breathing through the noseDamp/dripping noseNoise of machine Decreased mobilitySneezing

NHF 37C55120
NHF 41C95432

. On a five-point Likert scale, values close to one are favourable and values close to five are less favourable;   values by McNemar’s exact test, confidence intervals by asymptotic method. The same participant could be counted twice if they made the same comment for each intervention.