Sequencing Alpha-1 MZ Individuals Shows Frequent Biallelic Mutations

Table 1

Participant characteristics, N= 103.

Gender	N (%)	Average Age (range)
Female	78 (75.7)	53.9 ± 12.2 (25-73)
Male	25 (24.3)	46.4 ± 15.9 (18-73)
Smoking History
Ever-smoker	41 (39.8)
Female	31	53 ± 12.0 (25-71)
Male	10	56 ± 10.7 (34-73)
Never-smoker	62 (60.2)
Female	47	54 ± 12.1 (27-73)
Male	15	40 ± 14.9 (18-69)
Recruited From
Alpha-1 Coded Testing Study	59 (57.3)
Alpha-1 Foundation Research Registry or Clinicaltrials.gov	44 (42.7)