TY - JOUR
A2 - Gregoire, Francine M.
AU - Wang, Nanping
PY - 2008
DA - 2009/01/06
TI - PPAR- in Vascular Pathophysiology
SP - 164163
VL - 2008
AB - Peroxisome proliferator-activated receptors belong to the superfamily of ligand-dependent nuclear receptor transcription factors, which include three subtypes: PPAR-α, β/δ, and γ. PPAR-δ, play important roles in the regulation of cell growth and differentiation as well as tissue wound and repair. Emerging evidence has also demonstrated that PPAR-δ is implicated in lipids and glucose metabolism. Most recently, the direct effects of PPAR-δ on cardiovascular processes such as endothelial function and angiogenesis have also been investigated. Therefore, it is suggested that PPAR-δ may have critical roles in cardiovascular pathophysiology and is a potential target for therapeutic intervention of cardiovascular disorders such as atherosclerosis.
SN - 1687-4757
UR - https://doi.org/10.1155/2008/164163
DO - 10.1155/2008/164163
JF - PPAR Research
PB - Hindawi Publishing Corporation
KW -
ER -