Peroxisome Proliferator-Activated Receptor-𝛾 Is a Potent Target for Prevention and Treatment in Human Prostate and Testicular Cancer

Figure 4

Effects of PPAR-𝛾 ligands on apoptosis by flow cytometry in PC and TC cell lines. PC cells (PC3) and TC cell (NEC-8) lines with treatment of 25 𝜇M 15-d-PGJ₂ could induce early apoptosis not late apoptosis or necrosis. The higher left quadrants represent early apoptosis (Annexin V-FITC-positive cells and PI-negative cells). The higher right quadrants represent late apoptosis or necrosis (Annexin V-FITC-positive cells and PI-positive cells). Diagrams of FITC-Annexin V/PI flow cytometry are presented.

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