PPAR Research / 2008 / Article / Fig 1

Research Article

Improved Insulin Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors

Figure 1

CE reduced the fasted blood glucose level and improved glucose tolerance in DIO and mice. Mice were administered vehicle alone, or CE (equivalent to 400 mg cinnamon powder ) for 3 weeks (DIO) or 2 weeks ( ). The blood glucose levels were measured in tail vein and the basal glucose levels were shown at 0 minute. (a) DIO C57BL/6J mice were fasted overnight and glucose levels were measured at 9:00 am at the end treatment. NF: normal food fed mice; HF: high-fat food-induced mice; CE: cinnamon water extract; (b) fasted DIO mice were intraperitoneally injected with 2 g body weight and glucose tolerance determined at the time indicated; (c) Mice were fasted for 6 hours and the fasted blood glucose was measured. CONT: vehicle; (d) glucose tolerance was determined following 2 g body weight intraperitoneal injection in mice. The data are presented as mean ± SE, for each group. (b) versus HF group or (d) vehicle control (cont).