Improved Insulin Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors
Figure 1
CE reduced the fasted blood glucose level and
improved glucose tolerance in DIO and mice. Mice were
administered vehicle alone, or CE (equivalent to 400 mg cinnamon powder ) for 3 weeks
(DIO) or 2 weeks (). The blood glucose levels were
measured in tail vein and the basal glucose levels were shown at 0 minute. (a)
DIO C57BL/6J mice were fasted overnight and glucose levels were measured at 9:00 am at the end treatment. NF: normal food fed mice; HF: high-fat food-induced mice; CE:
cinnamon water extract; (b) fasted DIO mice were intraperitoneally injected with 2 g body weight and glucose tolerance determined at the time indicated; (c) Mice
were fasted for 6 hours and the fasted blood glucose was measured. CONT: vehicle;
(d) glucose tolerance was
determined following 2 g body weight intraperitoneal injection in mice. The data are
presented as mean ± SE, for each group. (b) versus HF group or (d) vehicle control (cont).
