Research Article

Regulation of Peroxisome Proliferator-Activated Receptors by E6-Associated Protein

Figure 1

E6-AP inhibits the transcriptional activity of PPAR , PPAR , and PPAR . 293T cells were transfected with plasmids expressing 4X-ACO-Luciferase, pRLCMV, PPAR , PPAR or PPAR , and E6-AP. Cells were lysed and luciferase activity was corrected for transfection efficiency and protein. Asterisks indicate a significant difference in luciferase values when compared to the 0 ratio group. (* with statistical analysis using ANOVA). The graphs are representative of 3 independent experiments.
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