The Role of PPARs in the Endothelium: Implications for Cancer Therapy
Figure 1
The endothelial cell is the interface between the circulation and underlying tissue, and as
such plays an important homeostatic role both producing and responding to a
variety of pro- and antiangiogenic, inflammatory, and coagulation factors. The
balance between these opposing pathways is critical in the growth, development,
spread, and metastasis of tumours.
