MBX-102/JNJ39659100, a Novel Non-TZD Selective Partial PPAR- Agonist Lowers Triglyceride Independently of PPAR- Activation
Figure 8
Effect of MBX-102 (200 mg/kg) and WY-14643
(130 mg/kg) on plasma triglyceride
levels (a), FFA levels (b), and liver weights (c) in WT and KO mice after 7 days
treatment of PPAR- KO mice. Values
represent mean SEM (: , : versus Vehicle, 2-way
ANOVA, and Bonferroni post-tests).