Peroxisome Proliferator-Activated Receptor -β/δ, -γ Agonists and Resveratrol Modulate Hypoxia Induced Changes in Nuclear Receptor Activators of Muscle Oxidative Metabolism
Figure 4
Protein level of SIRT1 (a), PGC-1α (b), and PPAR-γ (c) normalized to β-tubulin at Day 0, 2, 5, and 8 under three oxygen regimes: control 21%, 5%, and 1%. Values represent the mean of 4-5 experiments. . Representative blots are shown. ANOVA, # and ##significant from Day 0 within 21% oxygen ( and ), *significant between respective 21% oxygen time point and corresponding hypoxic time point ().
