Peroxisome Proliferator-Activated Receptor -β/δ, -γ Agonists and Resveratrol Modulate Hypoxia Induced Changes in Nuclear Receptor Activators of Muscle Oxidative Metabolism
Figure 5
The effect of PPAR-β/δ agonist (L165,041, 10 μM) treatment for 24 hours, following 7 days of differentiation under relative oxygen regimes, 21%, 5%, and 1%. Fold expression of RXR-α (a), UCP-2 (b), and CPT-1b (c) mRNA with (+) and without (−) L165,041. Values represent the mean of 4-5 experiments. . The effect of L165,041 within each oxygen regime was evaluated by Students -test, *, **, ***.
