PPAR Research / 2010 / Article / Tab 4

Research Article

Developmental Effects of Perfluorononanoic Acid in the Mouse Are Dependent on Peroxisome Proliferator-Activated Receptor-Alpha

Table 4

Serum PFNA concentrations at weaning in PPARα-KO and WT Adult female mice and offspring exposed to PFNA on GD 1–18.

StrainDose (mg/kg/day) Adult females with no live pups Adult females with live pups Pups (sexes combined)
PFNA ( g/ml) PFNA ( g/ml) littersPFNA ( g/ml)

014
0.8313
WT1.126
1.523
2.026

09
0.838
KO1.111
1.537
2.023

Values are means SEM or litter means SEM. Serum was collected from all adult females and from 2 pups per litter at 23 days post dose.
WT: wild type; KO: PPAR knockout.
Significantly different from control values by . See text for more statistical comparisons.

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