Virtual Screening as a Technique for PPAR Modulator Discovery

Table 1

PDB IDs of published crystal and NMR structures for PPAR $\gamma$ with various ligands bound. Resolution values are in Angstroms (Å). The “Reference number” columns list references for each PDB ID. The citations for these are present in the reference section. All PDB IDs list Homo sapiens as the protein source except 1ZGY (Rattus norvegicus). Access date: 23 March 2009.

Structure ID	Resolution (Å)	Release date	Reference number	Structure ID	Resolution (Å)	Release date	Reference number
1FM6	2.1	02/16/01	[6]	2Q6S	2.4	10/23/07	[23]
1FM9	2.1	02/16/01	[6]	2Q8S	2.3	10/14/08	[24]
1I7I	2.3	03/09/02	[25]	2QMV	n/a (NMR)	09/02/08	[26]
1K74	2.3	12/05/01	[27]	2VSR	2.0	08/19/08	[5]
1KNU	2.5	12/19/02	[28]	2VST	2.3	08/19/08	[5]
1NYX	2.7	07/15/03	[29]	2VV0	2.5	08/19/08	[5]
1PRG	2.2	01/13/01	[13]	2VV1	2.2	08/19/08	[5]
1RDT	2.4	11/09/04	[30]	2VV2	2.8	08/19/08	[5]
1WM0	2.9	09/07/04	[31]	2VV3	2.8	08/19/08	[5]
1ZEO	2.5	04/25/06	[32]	2VV4	2.3	08/19/08	[5]
1ZGY	1.8	07/26/05	[33]	2ZK0	2.4	2/24/09	[16]
2ATH	2.3	08/25/06	[34]	2ZK1	2.6	2/24/09	[16]
2F4B	2.1	02/14/06	[35]	2ZK2	2.3	2/24/09	[16]
2FVJ	2.0	05/16/06	[36]	2ZK3	2.6	2/24/09	[16]
2G0G	2.5	05/16/06	[37]	2ZK4	2.6	2/24/09	[16]
2G0H	2.3	05/16/06	[37]	2ZK5	2.5	2/24/09	[16]
2GTK	2.1	09/26/06	[38]	2ZK6	2.4	2/24/09	[16]
2HFP	2.0	09/19/06	[39]	3B3K	2.6	10/28/08	[40]
2HWQ	2.0	08/07/07	[41]	3BC5	2.3	11/18/08	[42]
2HWR	2.3	08/07/07	[41]	3CDP	2.8	1/13/09	[43]
2I4J	2.1	04/17/07	[17]	3CDS	2.7	12/30/08	[40]
2I4P	2.1	04/17/07	[17]	3CS8	2.3	06/03/08	[44]
2I4Z	2.3	04/17/07	[17]	3CWD	2.4	07/08/08	[45]
2OM9	2.8	04/24/07	[46]	3D24	2.1	06/10/08	[47]
2P4Y	2.3	01/08/08	[48]	3D6D	2.4	12/30/08	[40]
2POB	2.3	03/18/08	[49]	3DZU	3.2	10/28/08	[21]
2PRG	2.3	07/19/99	[13]	3DZY	3.1	10/28/08	[21]
2Q59	2.2	10/23/07	[23]	3E00	3.1	10/28/08	[21]
2Q5P	2.3	10/23/07	[23]	3ET0	2.4	2/17/09	[50]
2Q5S	2.0	10/23/07	[23]	3ET3	2.0	2/17/09	[50]
2Q61	2.2	10/23/07	[23]	3PRG	2.9	08/30/99	[3]
2Q6R	2.4	10/23/07	[23]	4PRG	2.9	05/27/99	[51]